Clinical Trials Open to Healthy Volunteers

A “healthy volunteer” is someone who doesn't have any major health problems, and takes part in research to test new medicines, devices, or treatments. UC Irvine offers clinical trials on a wide range of medical conditions. Healthy volunteers can help UC Irvine researchers make better comparisons to better understand the treatment of diseases.

• Acoustic and Electrical Stimulation for the Treatment of Tinnitus

  • study on Tinnitus
  • open to healthy people ages 18 years and up

• Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

  • study on Mild Cognitive Impairment and Alzheimer's Disease
  • open to healthy people ages 55-90

• Animal Assisted Intervention With Dogs for Children With ADHD

  • study on Attention-Deficit/Hyperactivity Disorder
  • open to healthy people ages 7-9

• Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)

  • study on Pregnancy and Anticoagulants
  • open to healthy females ages 18 years and up

• Breath Analysis in Early Stage Lung Cancer Using Infrared Spectroscopy

  • study on Lung Cancer and Non-Small Cell Lung Cancer
  • open to healthy people ages 18 years and up

• Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)

  • study on Dementia and Frontotemporal Dementia
  • open to healthy people ages 18 years and up

• Childhood Cancer Survivor Study

  • study on Cancer, General
  • open to healthy people

• Dementia Family Caregiver Study

  • study on Caregivers and Dementia
  • open to healthy people ages 18 years and up

• Dietary Sodium Intake and Blood Pressure in Living Kidney Donors

  • study on High Blood Pressure and Kidney Transplant
  • open to healthy people ages 18 years and up

• Effects of Mouthrinses on the Microbiome of the Oral Cavity and GI Tract

  • study on Oral Bacterial Infection and Oral Infection
  • open to healthy people ages 18 years and up

• Emotion-Diet Interactions in Pregnancy

  • study on Pregnancy and Mental Health
  • open to healthy females ages 18-40

• Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

  • study on Huntington's Disease
  • open to healthy people ages 18 years and up

• Ethnic Influences on Stress, Energy Balance and Obesity in Adolescents

  • study on Obesity and Mental Health
  • open to healthy females ages 13-17

• Evaluating the Efficacy of the Melanocyte Keratinocyte Transplantation Procedure in the Treatment of Vitiligo

  • study on Vitiligo
  • open to healthy people ages 18 years and up

• Exercise in Child Health

  • study on Cystic Fibrosis and Fibrosis
  • open to healthy people ages 10-17

• The Heart of the Community Study

  • study on Heart Rate Variability
  • open to healthy people ages 18 years and up

• Heartrate and Breathing Effects on Attention and Memory

  • study on Aging and Alzheimer's Disease
  • open to healthy people ages 50-70

• Imaging-based Assessment of Oral Biofilm and Gingival Health

  • study on Dental Plaque and Gingivitis
  • open to healthy people ages 18 years and up

• Intermuscular Coherence as a Biomarker for ALS

  • study on Amyotropic Lateral Sclerosis (ALS)
  • open to healthy people ages 20-80

• Intradetrusor Botulinum Toxin A: Are Less Injections Better?

  • study on Overactive Bladder and Urge Incontinence
  • open to healthy females ages 18 years and up

• Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE)

  • study on Atypical Hyperplasia of the Breast and Breast Cancer
  • open to healthy people

• MRI and PET Biomarkers for Cognitive Decline in Older Adults

  • study on Alzheimer's Disease and Cognitive Impairment
  • open to healthy people ages 60-105

• Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

  • study on Basal Cell Carcinoma and Carcinoma
  • open to healthy people ages 18-99

• Optical Sensor for Photodynamic Detection of Oral Pathology

  • study on Mouth Diseases
  • open to healthy people ages 18-75

• Patient Observational Pain and Activity Survey (POPAS) Study Using RS-4i Sequential Stimulator With Intersperse Technology in Axial Spine and Peripheral Joint Pain

  • study on Osteoarthritis
  • open to healthy people ages 18-89

• Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

  • study on Skin Lesion
  • open to healthy people

• Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects

  • study on Risk-Taking and Adolescent Behavior
  • open to healthy people ages 11-14

• Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

  • study on Muscle Atrophy and Osteoarthritis
  • open to healthy people ages 50-75

• Skin Imaging With Technologies in Development

  • study on Pigmented Skin Lesion of Uncertain Nature
  • open to healthy people ages 7 years and up

• SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow

  • study on Skin Laxity
  • open to healthy people ages 35-80

• SSIs for Mental Health and Loneliness

  • study on Loneliness and Mental Health
  • open to healthy people ages 16 years and up

• Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

  • study on HIV/AIDS and Cancer, General
  • open to healthy people ages 18 years and up

• Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC

  • study on Lung Cancer and Non-Small Cell Lung Cancer
  • open to healthy people ages 18 years and up

• TRC-PAD Program: In-Clinic Trial-Ready Cohort

  • study on Alzheimer's Disease and Dementia
  • open to healthy people ages 50-85

• Trigger Point Injections Versus Lidocaine Patch for Myofascial Pain in the Emergency Department

  • study on Myofascial Trigger Point Pain and Myofacial Pain
  • open to healthy people ages 18 years and up

• Understanding Individual Differences in Working Memory Training and Transfer in Older Adults

  • study on Cognitive Change
  • open to healthy people ages 50-85

• Using Nicotine to Reverse Age-related Auditory Processing Deficits

  • study on Auditory Perceptual Impairment and Aging
  • open to healthy people ages 18-85

• Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

  • study on Breast Cancer
  • open to healthy females ages 40-74