Summary

Eligibility
for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
Location
at Irvine, California
Dates
study started
completion around
Principal Investigator
by Anthony Durkin, PhD
Headshot of Anthony Durkin
Anthony Durkin

Description

Summary

The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimulate blood flow dynamic that these instruments are designed to sense. The researcher currently plan to assess only basic feasibility of the imaging instruments.

Official Title

A Pilot Study to Evaluate Multi-Spectral Imaging (MI) and Laser Speckle Imaging (LSI) and Multiphoton Microscopy (MPM) During Vascular Occlusion

Details

The primary reason for including pressure cuff occlusion in this protocol is to test the performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to hyperemic (over-perfused and over-saturated).

  1. Modulated Imaging a non-contact optical imaging technology can detect the concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute amounts in units of millimoles / unit volume of tissue measured.
  2. Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent light source, camera, and image acquisition system. This image device can measure and compare relative flow in vasculature at varied time points.

Keywords

Abnormal Vascular Flow, Multi-Spectral and Laser Speckle Imaging, Vascular Occlusion

Eligibility

You can join if…

Open to people ages 18 years and up

- Male and female adult 18 years and older

You CAN'T join if...

  • Younger than 18 years of age
  • Pregnant women

Location

  • Beckman Laser Institute and Medical Clinic accepting new patients
    Irvine California 92612 United States

Lead Scientist at UC Irvine

  • Anthony Durkin, PhD
    Associate Professor, Biomedical Engineering, Samueli School of Engineering. Authored (or co-authored) 98 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT01484730
Study Type
Observational
Participants
Expecting 100 study participants
Last Updated