Does Single Injection Adductor Canal Block Improve Postoperative Analgesia in Patients Receiving Periarticular Local Anesthesia Injections for Total Knee Arthroplasty?

a study on PainAnesthesia

Summary

for people ages 18 years and up (full criteria)
at Orange, California
study started
estimated completion
Coral Sun

Description

Summary

The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).

Keywords

Pain Managementpain management for total knee arthroplastyPharmaceutical SolutionsRopivacaineEpinephrineRacepinephrineEpinephryl borateKetorolacKetorolac TromethamineClonidineACB Control - 20 ml saline injection for ACBACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal BlockLocal infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal salineACB Study + Local infiltrationACB Study Only

Eligibility

You can join if…

Open to people ages 18 years and up

  • Males and Females age 18+ years old having total knee arthroplasty (TKA) at UCI Medical Center
  • American Society of Anesthesiologists physical status I to III

You CAN'T join if...

  • Allergy to local anesthetics
  • Pregnancy
  • Nursing Mothers
  • Children <18 years of age
  • Renal impairment (GFR<60 mL/min/1.73m2)
  • Hepatic Impairment (active hepatitis, elevated AST or ALT, jaundice)
  • Opioid tolerant patients (defined as greater than 30 mg Morphine equivalent consumed daily)
  • Patients that are diabetic with peripheral neuropathy
  • BMI greater than 40

Location

  • University of California, Irvine Medical Centeraccepting new patients
    OrangeCalifornia92868United States

Lead Scientist

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT02276495
Study Type
Interventional
Last Updated