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Age-related Cognitive Decline clinical trials at UC Irvine

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  • Heartrate and Breathing Effects on Attention and Memory

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    In the current study, we will examine how daily paced breathing affects plasma amyloid beta levels and the rate of learning in older adults. Healthy adults aged 50-70 who meet all eligibility criteria will be invited to this study. Participants will be randomly assigned to one of the two conditions: 1) Daily memory and attention training followed by a paced breathing protocol designed to increase relaxation or 2) Daily memory and attention training followed by a paced breathing protocol to increase alertness. Participants will be asked to complete pre and post intervention cognitive testing online, engage in 10 weeks of daily brain training (starting Week 2) and 9 weeks of paced breathing (starting Week 3) at home and to come in for lab visits to provide blood and urine samples on Weeks 2, 7 and 12 to allow for assessment of amyloid beta levels.

    Los Angeles, California

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