Peripheral Artery Disease clinical trials at UC Irvine
5 in progress, 1 open to eligible people
VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease
open to eligible people ages 18 years and up
VictORION-INCLUSION (V-INCLUSION) seeks to evaluate the effectiveness of inclisiran as an innovative therapy with the potential to help bridge care gaps in historically understudied and undertreated populations by leveraging electronic health records (EHR) in multiple US Healthcare Systems (HCS) to systematically identify those at high risk for and already diagnosed with ASCVD for more expeditious achievement of LDL-C targets.
Orange, California and other locations
Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System for the TREatment of Vascular Lesions Located in the InfrapoplitEal Arteries BeLow the Knee (DEEPER REVEAL)
Sorry, in progress, not accepting new patients
This is a prospective, multicenter, single arm study designed to evaluate the safety and efficacy of the Temporary Bare Spur Stent System (Spur Stent System).
Orange, California and other locations
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
Sorry, in progress, not accepting new patients
The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants with atherosclerotic cardiovascular disease (ASCVD) and elevated Lipoprotein(a).
Orange, California and other locations
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Sorry, in progress, not accepting new patients
Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery in older adults.
Irvine, California and other locations
Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease
Sorry, in progress, not accepting new patients
Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).
Irvine, California and other locations
Our lead scientists for Peripheral Artery Disease research studies include Ailin Barseghian, MD.
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