Vaso-Occlusive Crisis clinical trials at UC Irvine
2 in progress, 1 open to eligible people
CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
open to eligible people ages 12 years and up
This study consists of two parts: phase 2 (Part A) and phase 3 (Part B). It is a multicenter study designed to evaluate the safety, effectiveness, and pharmacokinetics (PK) of CSL889 (human hemopexin) when given intravenously (IV) to adults and adolescents with sickle cell disease (SCD) experiencing vaso-occlusive crises (VOC). The main objectives of the study are to assess how CSL889 affects the time it takes for VOC to resolve in participants with SCD, and to evaluate the safety and tolerability of CSL889 in study participants.
Orange, California and other locations
Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease
Sorry, in progress, not accepting new patients
This study is an open-label study to evaluate the safety of long-term administration of inclacumab in participants with sickle cell disease (SCD). Participants in this study will have completed a prior study of inclacumab.
Orange, California and other locations
Last updated: