Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Irvine, California
Dates
study started
completion around

Description

Summary

The goal of this clinical trial is to determine whether monitoring intra-abdominal pressure (IAP) and adjusting blood pressure accordingly to maintain optimal renal perfusion pressure can reduce the risk of acute kidney injury (AKI) after cardiac surgery.

The main question this study aims to answer is:

  • Does IAP-guided blood pressure management improve renal perfusion and lower AKI rates in cardiac surgery patients?

Participants will be randomly assigned to one of two groups:

  • Control Group: Standard ICU care with a conventional Foley catheter.
  • Intervention Group: Standard ICU care with an IAP-monitoring Foley catheter, where blood pressure is adjusted based on IAP readings to optimize renal perfusion pressure.

All participants will undergo routine blood and urine tests to assess kidney function during their hospital stay.

This study will help determine whether IAP-based hemodynamic management can improve postoperative kidney outcomes and provide a new strategy for AKI prevention in cardiac surgery patients.

Official Title

Use of an Intraabdominal Pressure Monitoring Urinary Catheter After Cardiac Surgery to Improve Kidney Perfusion Pressure: A Randomized Controlled Trial

Keywords

Acute Kidney Injury, Intra-Abdominal Pressure, Renal Perfusion Pressure, Cardiac Surgery, Accuryn Foley Catheter

Eligibility

You can join if…

Open to people ages 18 years and up

  • Adults Undergoing cardiac surgery with cardiopulmonary bypass
  • Left ventricular ejection fraction (LVEF) < 50%

You CAN'T join if...

Location

  • UCI Medical Center
    Irvine California 92868 United States

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
Dang Tan Phat
ID
NCT06989762
Study Type
Interventional
Participants
Expecting 100 study participants
Last Updated