Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Irvine, California and other locations
Dates
study started
completion around

Description

Summary

The focus of this prospective observational study is to (1) establish the range and variation associated with bone/soft tissue perfusion in fracture patients, using ICG fluorescence imaging; (2) examine the relationship between perfusion and complications such as surgical site infection (SSI), persistent SSI, and fracture nonunion; (3) to determine whether the quantitative ICG fluorescence can be used to guide bony debridement in the setting of infected fracture to minimize complications.

Official Title

Real-time Fluorescence-based Measurement of Bone Perfusion in Post-traumatic Infection

Details

Keywords

Trauma Injury, Immunofluorescence, Orthopaedic, Trauma, Infection, Infections, Immunofluorescence Imaging, DCE-MRI

Eligibility

Locations

  • University of California, Irvine
    Irvine California 92614 United States
  • University of Maryland, Baltimore R. Adams Cowley Shock Trauma
    Baltimore Maryland 21201 United States
  • Dartmouth Hitchcock Medical Center
    Lebanon New Hampshire 03756 United States
  • Brigham and Women's Hospital
    Boston Massachusetts 02115 United States

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Dartmouth-Hitchcock Medical Center
ID
NCT04403204
Study Type
Observational [Patient Registry]
Participants
Expecting 170 study participants
Last Updated