Summary

Eligibility
for people ages 10-17 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at Irvine, California
Dates
study started
completion around

Description

Summary

The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, studies will be conducted in adults and separately in children and adolescents. The UC Irvine MoTrPAC Pediatric Clinical Center oversees two interrelated study phases in children and adolescents:

  1. A cross-sectional phase in which molecular transducers (obtained from blood sampling) are measured in response to an acute exercise challenge (n = 320);
  2. An intervention phase is conducted as a mechanistic randomized controlled trial (RCT). Participants are recruited from the cross-sectional study phase and randomized to endurance exercise (EE) training (n = 120) or no exercise Control (n = 50) for a period of approximately 12 weeks.

Details

Keywords

Physical Activity, EE Training, Endurance Exercise, Cross Sectional HA, Cross Sectional LA

Eligibility

Location

  • University of California, Irvine
    Irvine California 92697 United States

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Wake Forest University Health Sciences
ID
NCT04151199
Study Type
Interventional
Participants
Expecting 320 study participants
Last Updated