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Multiple Sclerosis clinical trials at UC Irvine

2 in progress, 0 open to eligible people

Showing trials for
  • Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

    Sorry, not currently recruiting here

    A study to evaluate the efficacy and safety of fenebrutinib on disability progression and relapse rate in adult participants with RMS. Eligible participants will be randomized 1:1 to either fenebrutinib or teriflunomide. Open-Label Extension (OLE) phase is contingent on a positive benefit-risk result in the Primary Analysis of the study.

    Irvine, California and other locations

  • Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

    Sorry, in progress, not accepting new patients

    This is a randomized, double blind, controlled, parallel group, multicenter study to evaluate efficacy, safety and pharmacokinetics of a higher dose of ocrelizumab per intravenous (IV) infusion every 24 weeks in participants with PPMS, in comparison to the approved 600 mg dose of ocrelizumab.

    Irvine, California and other locations

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