This study is in progress, not accepting new patients

The INSPIRE-ASP UTI Trial

a study on Urinary Tract Infection

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Riverside, California and other locations
Dates
study started
completion around
Principal Investigator
by Susan Huang, MD, MPH

Description

Summary

The INSPIRE-ASP UTI trial is a cluster-randomized controlled trial of HCA hospitals comparing routine empiric antibiotic stewardship practices with real-time precision medicine computerized physician order entry smart prompts providing the probability that a non-critically ill adult admitted with UTI is infected with a resistant pathogen.

Note: that enrolled "subjects" represents 59 individual HCA hospitals that have been randomized.

Official Title

INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients With Urinary Tract Infections (UTI): The INSPIRE-ASP UTI Trial

Keywords

Urinary Tract Infection (UTI), UTI, CPOE, Empiric Therapy, Infections, Urinary Tract Infections, Routine Care, INSPIRE CPOE Smart Prompt

Eligibility

For people ages 18 years and up

Facility Inclusion Criteria:

  • HCA hospitals admitting adults for UTI
  • Facility use of MEDITECH as their electronic health record system

Facility Exclusion Criteria:

  • Note: unit of randomization is the hospital, however the CPOE alert intervention will calculate risk estimates for adults age >=18 admitted to non-ICU wards and who are ordered to receive extended-spectrum antibiotics for UTI.

Locations

  • Riverside Community Hospital
    Riverside California 92501 United States
  • Los Robles Regional Medical Center
    Thousand Oaks California 91360 United States

Lead Scientist at UC Irvine

  • Susan Huang, MD, MPH
    Professor, Medicine, School of Medicine. Authored (or co-authored) 202 research publications

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Harvard Pilgrim Health Care
ID
NCT03697096
Study Type
Interventional
Participants
Expecting 59 study participants
Last Updated