Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Riverside, California and other locations
Dates
study started
estimated completion
Principal Investigator
Susan Huang, MD, MPH

Description

Summary

The INSPIRE-ASP PNA trial is a cluster-randomized controlled trial of HCA hospitals comparing routine empiric antibiotic stewardship practices with real-time precision medicine computerized physician order entry smart prompts providing the probability that a non-critically ill adult admitted with PNA is infected with a resistant pathogen. Note: that enrolled "subjects" represents 59 individual HCA hospitals that have been randomized.

Official Title

INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients With Pneumonia: The INSPIRE-ASP PNA Trial

Keywords

Pneumonia PNA CPOE Empiric Therapy INSPIRE CPOE Smart Prompt Routine Care

Eligibility

For people ages 18 years and up

Facility Inclusion Criteria:

  • HCA hospitals admitting adults with PNA
  • Facility use of MEDITECH as their electronic health record system

Facility Exclusion Criteria:

-

Note: unit of randomization is the hospital, however the CPOE alert intervention will calculate risk estimates for adults age >=18 admitted to non-ICU wards and who are ordered to receive extended-spectrum antibiotics for PNA.

Locations

  • Riverside Community Hospital accepting new patients
    Riverside California 92501 United States
  • Los Robles Regional Medical Center accepting new patients
    Thousand Oaks California 91360 United States

Lead Scientist at UC Irvine

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Harvard Pilgrim Health Care
ID
NCT03697070
Study Type
Interventional
Last Updated