Summary

for people ages 18 years and up (full criteria)
at Riverside, California and other locations
study started
estimated completion
Susan Huang

Description

Summary

The INSPIRE-ASP PNA trial is a cluster-randomized controlled trial of HCA hospitals comparing routine empiric antibiotic stewardship practices with real-time precision medicine computerized physician order entry smart prompts providing the probability that a non-critically ill adult admitted with PNA is infected with a resistant pathogen. Note: that enrolled "subjects" represents 59 individual HCA hospitals that have been randomized.

Official Title

INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients With Pneumonia: The INSPIRE-ASP PNA Trial

Keywords

Pneumonia PNA CPOE Empiric Therapy Anti-Bacterial Agents Antibiotics, Antitubercular INSPIRE CPOE Smart Prompt Routine Care

Eligibility

For people ages 18 years and up

Facility Inclusion Criteria:

  • HCA hospitals admitting adults for PNA
  • Facility use of MEDITECH as their electronic health record system

Facility Exclusion Criteria:

-

Note: unit of randomization is the hospital, however the CPOE alert intervention will calculate risk estimates for adults age >=18 admitted to non-ICU wards and who are ordered to receive extended-spectrum antibiotics for PNA.

Locations

  • Riverside Community Hospital accepting new patients
    Riverside California 92501 United States
  • Los Robles Regional Medical Center accepting new patients
    Thousand Oaks California 91360 United States

Lead Scientist

  • Susan Huang
    Professor, Medicine. Authored (or co-authored) 151 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Harvard Pilgrim Health Care
ID
NCT03697070
Study Type
Interventional
Last Updated