Summary

for people ages 18 years and up (full criteria)
at Garden Grove, California and other locations
study started
estimated completion
Susan Huang

Description

Summary

This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.

Keywords

Hospitalization Infection Nursing Homes Health Facilities Infections Readmissions Multi-Drug resistance Antibiotic Use Communicable Diseases Chlorhexidine Chlorhexidine gluconate Povidone-Iodine Povidone Chlorhexidine gluconate (CHG) Iodophor (10% povidone-iodine) Decolonization Routine Bathing

Eligibility

You can join if…

Open to people ages 18 years and up

Nursing homes will be eligible to participate if they meet the following criteria:

  • Licensed nursing home in Orange County or Southern Los Angeles County serving adults
  • Minimal use of chlorhexidine bathing*
  • Minimal use of nasal decolonization Minimal use defined as <15% of residents receiving at least one chlorhexidine bath or nasal decolonization treatment during their nursing home stay.

You CAN'T join if...

Nursing homes will not be eligible to participate if they meet the following criteria:

  • Facilities routinely using decolonization
  • Dedicated psychiatric nursing homes
  • Facilities with a resident population with >=20% combative patients
  • Pediatric facilities

Note: in any participating nursing home, residents with active end-of-life comfort care only measures are excluded

Locations

  • Pacific Haven Subacute Healthcare Center accepting new patients
    Garden Grove California 92843 United States
  • Buena Vista Care Center accepting new patients
    Anaheim California 92802 United States
  • Walnut Village Rehabilitation and Care Center accepting new patients
    Anaheim California 92802 United States

Lead Scientist

  • Susan Huang
    Professor, Medicine. Authored (or co-authored) 151 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT03118232
Phase
Phase 4
Study Type
Interventional
Last Updated