This study is in progress, not accepting new patients

Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

a study on Hospitalization Infection

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Garden Grove, California and other locations
Dates
study started
estimated completion
Principal Investigator
by Susan Huang, MD MPH

Description

Summary

This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.

Keywords

Hospitalization, Infection, Nursing Homes, Health Facilities, Infections, Readmissions, Multi-Drug resistance, Antibiotic Use, Communicable Diseases, Chlorhexidine, Chlorhexidine gluconate, Povidone-Iodine, Povidone, Chlorhexidine gluconate (CHG), Iodophor (10% povidone-iodine), Decolonization, Routine Bathing

Eligibility

You can join if…

Open to people ages 18 years and up

Nursing homes will be eligible to participate if they meet the following criteria:

  • Licensed nursing home in Orange County or Southern Los Angeles County serving adults
  • Minimal use of chlorhexidine bathing*
  • Minimal use of nasal decolonization* *Minimal use defined as <15% of residents receiving at least one chlorhexidine bath or nasal decolonization treatment during their nursing home stay.

You CAN'T join if...

Nursing homes will not be eligible to participate if they meet the following criteria:

  • Facilities routinely using decolonization
  • Dedicated psychiatric nursing homes
  • Facilities with a resident population with >=20% combative patients
  • Pediatric facilities

Note: in any participating nursing home, residents with active end-of-life comfort care only measures are excluded

Locations

  • Pacific Haven Subacute Healthcare Center
    Garden Grove California 92843 United States
  • Buena Vista Care Center
    Anaheim California 92802 United States
  • Walnut Village Rehabilitation and Care Center
    Anaheim California 92802 United States
  • Anaheim Crest Nursing Center
    Anaheim California 92804 United States
  • Sun Mar Nursing Center
    Anaheim California 92804 United States
  • West Anaheim Extended Care
    Anaheim California 92804 United States
  • Capistrano Beach Care Center
    Capistrano Beach California 92624 United States
  • Windsor Gardens Care Center of Fullerton
    Fullerton California 92832 United States
  • Gordon Lane Care Center
    Fullerton California 92831 United States
  • Terrace View Care Center
    Fullerton California 92835 United States

Lead Scientist at UC Irvine

  • Susan Huang, MD MPH
    Professor, Medicine, School of Medicine. Authored (or co-authored) 192 research publications

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT03118232
Phase
Phase 4 research study
Study Type
Interventional
Participants
Expecting 28 study participants
Last Updated