Summary

for people ages 18-25 (full criteria)
at Irvine, California
study started
estimated completion
Beckman Laser Institute and Medical Center

Description

Summary

There is a need for toothpastes that more effectively remove oral plaque and prevent re-formation. The objective of this study is to map the development and resolution of clinical gingivitis using conventional clinical examination and imaging data to determine how useful imaging techniques can be for evaluating how well a toothpaste cleans the teeth

Details

The researcher can use imaging techniques to map changes in gingival blood flow during the development and resolution of fully reversible, early clinical gingivitis using standard-of-care clinical indices as gold standard

The researcher can use imaging techniques to map inflammatory microstructural changes in the oral mucosa including swelling, vasodilation and edema during the development and resolution of fully reversible, early clinical gingivitis using standard-of-care clinical indices as gold standard

Keywords

Gingivitisoptical measurements

Eligibility

You can join if…

Open to people ages 18-25

  • Adult male or female 18-25 years of age
  • Volunteers with gingivitis but no periodontitis

You CAN'T join if...

  • Subjects who must receive dental treatment during the study dates.
  • History of significant adverse effects following use of oral hygiene products such as toothpastes and mouth rinses. Allergy to personal care/consumer products or their ingredients.
  • Individuals who have taken antibiotics in the previous 3 months
  • Individuals who are pregnant or nursing

Location

  • Beckman Laser Instituteaccepting new patients
    IrvineCalifornia92612United States

Lead Scientist

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT02178046
Study Type
Observational [Patient Registry]
Last Updated