Trauma clinical trials at UC Irvine

4 in progress, 1 open to eligible people

Showing trials for

  • UltraMTP in Adult Trauma Patients Undergoing Surgery Within 24 Hours: Effects on Mortality and Clinical Outcomes

    open to eligible people ages 18 years and up

    The purpose of this study is to determine the effects of ultraMTP (>/=30 units pRBC within 24 hours) in trauma patients on mortality and secondary outcomes. The aim is to determine if there is a set number of pRBC units transfused in adult trauma patients undergoing surgery within 24 hours, after which mortality is inevitable and further transfusions are futile.

    Los Angeles, California

  • Empiric Calcium in Massive Transfusion

    Sorry, not yet accepting patients

    Calcium helps blood to clot and thereby stop bleeding. Trauma patients who experience large volume blood loss often require blood transfusions and bleeding is the most common cause of death. The purpose of this study is to see if giving intravenous calcium immediately to patients who require large volume blood transfusion will decrease transfusion requirements, vasopressor use and mortality in bleeding trauma patients.

  • Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma

    Sorry, in progress, not accepting new patients

    This study evaluates the use of the Human Acellular Vessel (HAV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery. There will be a torso cohort and a limb cohort. All subjects will be implanted with a HAV as an interposition vessel or bypass using standard vascular surgical techniques. There is no control arm.

    Orange, California and other locations

  • Induction Medications Used in the Trauma RSI

    Sorry, not yet accepting patients

    To compare the outcomes of the use of propofol, etomidate, and ketamine as induction agents for adult trauma patients undergoing intubation within 24 hours of admission. The primary goal is to determine the ideal agent that should be used in this patient population for intubations.

    Los Angeles, California

Our lead scientists for Trauma research studies include .

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