Tibial Fractures clinical trials at UC Irvine
1 research study open to eligible people
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
open to eligible people ages 18 years and up
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic inflammation and chronic pain. In animal and clinical trials, PEA has also shown evidence of pain reduction, sleep improvement, and increased joint mobility and function with minimal side-effects. The study team intends to study whether the inclusion of PEA in conjunction with standard post-surgical medications can reduce pain and inflammation while decreasing the number of opioids needed.
Our lead scientists for Tibial Fractures research studies include Ariana Nelson, MD.