Stroke clinical trials at UC Irvine

• Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

  open to eligible people ages 18 years and up

  Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes as measured by the modified Rankin Scale.

  Orange, California and other locations

• AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

  open to eligible people ages 45 years and up

  Objectives - Primary: To test the hypothesis that apixaban is superior to aspirin for the prevention of recurrent stroke in patients with cryptogenic ischemic stroke and atrial cardiopathy. - Secondary: To test the hypothesis that the relative efficacy of apixaban over aspirin increases with the severity of atrial cardiopathy.

  Orange, California and other locations

• Sleep for Stroke Management and Recovery Trial

  open to eligible people ages 18 years and up

  The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

  Orange, California and other locations

• FitMi Plus Home Therapy for Stroke Patients

  Sorry, not yet accepting patients

  The investigators will investigate the efficacy of a newly developed functional exercise device (FitMi Plus) for people in the chronic stage after a stroke compared to the FitMi Basic (i.e. without functional exercises). FitMi Plus combines objects commonly used during activities of daily living with sensors that can track and record the patient's direction and degree of movement as they perform specific functional tasks described on a computer.

  Irvine, California

• Wearable Device for Motivating Hand Use After Stroke

  Sorry, in progress, not accepting new patients

  The goal of this study is to determine the effectiveness of interactive feedback from a wearable device that senses hand function, the Manumeter, in improving upper extremity function in a pilot, randomized controlled trial with chronic stroke patients

  Irvine, California

Last updated: November 18, 2020