Stroke clinical trials at UC Irvine
10 in progress, 6 open to eligible people
Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
open to eligible people ages 40 years and up
The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.
Irvine, California and other locations
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
open to eligible people ages 18 years and up
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To…
Orange, California and other locations
Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
open to eligible people ages 18-84
The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit. This study will compare two different ways to perform the extra arm …
Orange, California and other locations
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial
open to eligible people ages 18-80
The objective of the rFVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial is to establish the first treatment for acute spontaneous intracerebral hemorrhage (ICH) within a time window and subgroup of patients that is…
Orange, California and other locations
Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net
open to eligible people ages 35 years and up
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical …
Downey, California and other locations
Sleep for Stroke Management and Recovery Trial
open to eligible people ages 18 years and up
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6…
Orange, California and other locations
Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Sorry, in progress, not accepting new patients
Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the last 72 hours had: - an acute stroke due to a blood clot that formed outside the heart (acute…
Orange, California and other locations
BCI-FES Therapy for Stroke Rehabilitation
Sorry, in progress, not accepting new patients
There are over 7 million stroke survivors in the US alone, with approximately 795,000 new cases annually. Despite the best available physiotherapy, 30-60% of stroke survivors remain affected by difficulty walking, with foot weakness often being the…
Irvine, California
Determinants of the Effectiveness of Robot-assisted Hand Movement Training
Sorry, in progress, not accepting new patients
The investigators would like to investigate the effectiveness of somatosensory training for robot-assisted hand motor rehabilitation after stroke.
Irvine, California
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
Sorry, in progress, not accepting new patients
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial infarction, ischemic…
Orange, California and other locations
Our lead scientists for Stroke research studies include David Reinkensmeyer, Ph.D An Do, MD.
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