Overactive Bladder clinical trials at UC Irvine

4 research studies open to eligible people

Showing trials for

  • Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

    open to eligible people ages 18 years and up

    The goal of this prospective, multicenter, single-arm study is to test the safety and effectiveness of eCoin ® tibial nerve stimulation in subjects having overactive bladder (OAB) with urgency urinary incontinence (UUI). The main questions it aims to answer are: - The proportion of subjects achieving at least a 50% improvement in the number of urgency urinary incontinence episodes on a 3-day voiding diary (72 hours) after 12 months of therapy. - The rate of device- or procedure-related AEs through 12 months post-activation of eCoin ®. Participants will be implanted with eCoin ® and complete voiding diaries and patient reported-outcomes through 12 months of eCoin ® therapy.

    Irvine, California and other locations

  • BlueWind RENOVA iStim™ System for the Treatment of OAB

    open to eligible females ages 18-80

    The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.

    Orange, California and other locations

  • CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology

    open to eligible people ages 18 years and up

    This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system. Subjects from both groups will immediately start with therapy. The primary endpoint is a ≥ 50% reduction in number of incontinence episodes associated with urgency at the 3-month visit, with additional measurements assessed at 14 days, 1, 6, 9 and 12-months.

    Orange, California and other locations

  • Intradetrusor Botulinum Toxin A: Are Less Injections Better?

    open to eligible females ages 18 years and up

    Patients with either overactive bladder (OAB) or urgency urinary incontinence (UUI) with be randomized (like a flip of a coin) to receive 100 units of bladder Botox® at either one injection site or ten injection sites. Efficacy and patient satisfaction will be measured by questionnaires.

    Orange, California

Our lead scientists for Overactive Bladder research studies include .

Last updated: