Muscular Atrophy clinical trials at UC Irvine

3 in progress, 1 open to eligible people

Showing trials for

  • Clinical Procedures to Support Research in ALS

    open to eligible people ages 18 years and up

    The purpose of the Clinical Procedures To Support Research (CAPTURE) study is to utilize information collected in the medical record to learn more about a disease called amyotrophic lateral sclerosis (ALS) and related disorders.

    Irvine, California and other locations

  • Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

    Sorry, in progress, not accepting new patients

    A multi-center, longitudinal, prospective, non-comparative study to investigate the long-term safety and effectiveness of risdiplam, prescribed based on clinician judgment as per the Evrysdi® U.S. Package Insert (USPI) in adult and pediatric participants with SMA. In this study, participants will be followed for the duration of the study or until withdrawal of consent, loss to follow-up, or death. Participants who discontinue risdiplam may still remain in the study, if they agree to continue participating in the follow-up assessments. An optional sub study will assess the feasibility, acceptability, and adherence of remote assessment of motor and bulbar functions in participants with SMA using wearable and smartphone-based biosensors. Approximately 39 participants from the main study are planned to be enrolled in the sub study.

    Orange, California and other locations

  • IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

    Sorry, in progress, not accepting new patients

    An open-label dose escalation study to assess the safety and tolerability of IMM01-STEM in participants with muscle atrophy related to knee osteoarthritis

    Orange, California and other locations

Our lead scientists for Muscular Atrophy research studies include .

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