Kidney Transplant clinical trials at UC Irvine
2 research studies open to eligible people
Dietary Sodium Intake and Blood Pressure in Living Kidney Donors
open to eligible people ages 18 years and up
This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake is superior to high dietary sodium intake in controlling blood pressure to be within the normotensive range in living kidney donors.
Orange, California
PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
open to eligible people ages 18 years and up
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outcomes of the historical control group (control arm) to determine Prospera's clinical utility. High-risk subjects defined as having a biopsy-demonstrated rejection event or at least one pre-existing Donor Specific Antibody DSA with total Mean Fluorescent Intensity MFI>3000 or a calculated Panel Reactive Antibodies cPRA>70% will be followed for an additional period up to 24 months in both the Prospera arm and historical control arm.
Irvine, California and other locations
Our lead scientists for Kidney Transplant research studies include Ekamol Tantisattamo, MD, MPH.
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