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Kidney Disease clinical trials at UC Irvine
4 in progress, 1 open to new patients

  • Comparison of the Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis

    open to eligible people ages 18 years and up

    The main purpose of this study is to compare the Human Acellular Vessel (HAV) with arteriovenous fistula (AVF) when used for hemodialysis access

    Irvine, California and other locations

  • A Pilot Feasibility Trial of Thyroid Hormone Replacement in Dialysis Patients

    Sorry, not yet accepting patients

    Hypothyroidism, defined by elevated thyrotropin (TSH) levels, is a common endocrine complication of chronic kidney disease that has been associated with impaired quality of life and cardiovascular complications. While levothyroxine is one of the most frequently prescribed medications in chronic kidney disease patients, little is known about its efficacy and safety in this population. This study will investigate 1) whether levothyroxine adequately lowers thyrotropin (TSH) levels to therapeutic target ranges, and 2) if thyroid hormone replacement improves quality of life and cardiovascular markers, without leading to wasting in dialysis patients.

  • Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe)

    Sorry, not yet accepting patients

    The purpose of this study is reduce episodes of intradialytic hypotension, low blood pressure during a hemodialysis session, in patients with End Stage Renal Disease (ESRD). Recruitment will take place on the clinic level rather than the patient level.

  • Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis

    Sorry, in progress, not accepting new patients

    The main purpose of this study is to compare the Human Acellular Vessel (HAV) with ePTFE grafts when used for hemodialysis access.

    Irvine, California and other locations

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