Hernia clinical trials at UC Irvine

2 in progress, 1 open to eligible people

Showing trials for

  • De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

    open to eligible people ages 0 months to 1 month

    The purpose of this study is to determine if de-implementation of inhaled nitric oxide (iNO) in the post-natal resuscitation/stabilization phase affects the composite outcome of extracorporeal life support (ECLS) use and/or mortality, as well as ECLS use, mortality, and/or oxygenation in congenital diaphragmatic hernia (CDH) newborns and to establish the cost-effectiveness of de-implementing iNO as a therapy in the postnatal resuscitation/stabilization phase of CDH management, which will be assessed as the incremental health system costs (savings) per prevented ECLS use and/or death.

    Irvine, California and other locations

  • Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair

    Sorry, in progress, not accepting new patients

    This single-blind randomized control study will follow 142 subjects across 7 sites randomized on a 1:1 ratio to compare treatment efficacy and safety between TIF and LNF in GERD patients with hiatal hernia undergoing hernia repair.

    Irvine, California and other locations

Our lead scientists for Hernia research studies include .

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