Heart Attack clinical trials at UC Irvine
2 in progress, 1 open to eligible people
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
open to eligible people ages 18-99
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial infarction, ischemic stroke, arterial revascularization, and all-cause death in subjects hospitalized for an acute myocardial infarction (non-ST-segment elevation myocardial infarction [NSTEMI] and ST-segment elevation myocardial infarction [STEMI]).
Orange, California and other locations
Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net
Sorry, not yet accepting patients
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are: - Do people in the REACH BP program have lower blood pressure at 12 months compared to those getting usual care? - Do people in the REACH BP program have better Life's Essential 8 scores and patient experience compared to those getting usual care? Half the participants will be randomly assigned to usual care and half will be assigned to the program. Those assigned to the program will receive a blood pressure cuff to check their blood pressure at home, educational materials, monthly phone calls from a health coach and regular follow up with a pharmacist who will prescribe medications, adjust them, and answer any questions and concerns. The health coach will teach the participants how to log on to the patient portal and access educational materials on an app. Those assigned to usual care will continue seeing their providers. All participants will be asked survey questions once they enroll, at 3 months and at 12 months.
Downey, California and other locations
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