Diabetes clinical trials at UC Irvine
7 in progress, 4 open to eligible people
Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness
open to eligible females ages 18 years and up
A pilot randomized control trial (RCT) to examine the efficacy of a culturally tailored mindfulness intervention upon fasting cardiometabolic factors (including markers of glycemic control) and inflammatory gene expression in n=60 (n=30…
Santa Ana, California
Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial
open to eligible people ages 18-99
This randomized controlled trial will investigate whether use of continuous glucose monitoring (CGM) vs. usual care with self-monitored blood glucose 1) enhances glycemic control, 2) reduces hypoglycemia risk, and 3) improves quality of life,…
Orange, California
Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
open to eligible people ages 18-99
The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
Orange, California and other locations
RAY121 in Immunological Diseases (RAINBOW Trial)
open to eligible people ages 18-85
This Phase 1b basket trial will investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity and preliminary efficacy of RAY121, a inhibitor of classical complement pathway, after multiple dose administration in patients…
Orange, California and other locations
Dexcom G6 Continuous Glucose Monitoring in Hemodialysis
Sorry, in progress, not accepting new patients
This is a pilot study enrolling adult hemodialysis patients with diabetes recruited from the University of California Irvine Medical Center (UCIMC) who will undergo simultaneous measurement of glucose levels using 1) continuous glucose monitor (CGM) …
Orange, California
Plant-Focused Nutrition in Patients With Diabetes and Chronic Kidney Disease
Sorry, accepting new patients by invitation only
In this pilot clinical trial, the investigators will recruit and randomize 120 patients with diabetes mellitus and chronic kidney disease (CKD/DM) stages 3 to 5 to a patient-centered and flexible Plant-Focused Nutrition in Diabetes (PLAFOND) diet…
Orange, California and other locations
AT-001 in Patients With Diabetic Cardiomyopathy
Sorry, in progress, not accepting new patients
This is a multicenter, randomized, placebo-controlled, 2-part study to evaluate the safety and efficacy of AT-001 in adult patients (N=675) with Diabetic Cardiomyopathy at high risk of progression to overt heart failure.
Orange, California and other locations
Our lead scientists for Diabetes research studies include Karen L Lindsay, RD, PhD Lauren E Gyllenhammer, PhD.
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