Degenerative Disc Disease clinical trials at UC Irvine

4 in progress, 2 open to eligible people

Showing trials for

  • DEXA-C Anterior Cervical Interbody System

    open to eligible people ages 18 years and up

    FDA Cleared interbody product for the cervical spine, designed to match a patients DEXA scan for increase in fusion rate.

    Orange, California and other locations

  • Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

    open to eligible people ages 18 years and up

    This is a phase IV post-marketing study for MagnetOs Easypack Putty. MagnetOs Easypack Putty is a synthetic bone graft extender product that is routinely used by surgeons as a treatment for patients with degenerative disc disease or spinal trauma undergoing spinal fusion surgery. In this study, MagnetOs Easypack Putty will be used according to the latest U.S. Instructions For Use, standalone in the posterolateral spine.

    Irvine, California and other locations

  • P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation

    Sorry, in progress, not accepting new patients

    The aim of this trial is to evaluate if P-15L bone graft (investigational device) is not inferior in effectiveness and safety to local autologous bone (and allograft where necessary) as an extender (control device) when applied in instrumented transforaminal lumbar interbody fusion (TLIF) in subjects with degenerative disc disease (DDD). In addition to the general overall objective, a sub-group analysis will be performed on the high-risk subject population (tobacco use, obesity, diabetes), as previous studies have shown negative effects of smoking, obesity and diabetes on fusion and bone healing, increased peri/postoperative complications, and lower patient-reported outcome scores.

    Orange, California and other locations

  • Posterior Cervical Fixation Study

    Sorry, accepting new patients by invitation only

    The objective of this study is to evaluate the safety and performance of occipito-cervico-thoracic spine surgery using posterior fixation as measured by reported complications, radiographic outcomes, and patients reported outcomes (PROs).This study is being undertaken to identify possible residual risks and to clarify mid-to long-term clinical performance that may affect the benefit/risk ratio of posterior fixation systems.

    Orange, California and other locations

Our lead scientists for Degenerative Disc Disease research studies include .

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