BRAF Gene Mutation clinical trials at UC Irvine
1 research study open to eligible people
Showing trials for
IK-595 in RAS- or RAF-altered Advanced Tumors
open to eligible people ages 18 years and up
This is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) effects, and preliminary antitumor activity of IK-595, a MEK/RAF molecular glue, administered orally as monotherapy in patients with advanced solid tumors with gene alterations in the RAS- MAPK pathway for whom there are no further treatment options known to confer clinical benefit.
Orange, California and other locations
Our lead scientists for BRAF Gene Mutation research studies include Jennifer Valerin, MD.
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