for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
at Orange, California
study started
estimated completion
Principal Investigator
by Bharath Chakravarthy, MD



The aim of this trial is to investigate the efficacy of trigger point injections with 1% lidocaine in reducing myofascial back and neck pain in the Emergency Department compared to lidocaine patches 5%.

Official Title

A Randomized Controlled Study Comparing Trigger Point Injections With 1% Lidocaine Versus 5% Lidocaine Patch for Myofascial Pain in the Emergency Department


After being informed about the study and the potential risks and benefits, all patients will be randomized into either the trigger point injection group with 1% lidocaine, or the 5% lidocaine patch group. Pain scores will be recorded while in the emergency department, and we will have a 5 day follow-up phone call to assess efficacy. Patients who present to UCI Department of Emergency medicine will be screened and recruited prospectively, and information regarding this study will be available on as a method of recruitment.


Myofascial Trigger Point Pain Myofacial Pain pain management emergency department trigger point injections lidocaine patches myofascial pain interventional pain medicine Myofascial Pain Syndromes Emergencies Facial Pain Lidocaine Trigger point injection with 1% lidocaine Lidocaine patch 5%


You can join if…

Open to people ages 18 years and up

  • 18 years or older
  • Diagnosed with myofascial pain of the posterior neck or back. *The diagnosis of myofascial pain was based on established criteria of having a palpable taut band (trigger point) that when depressed reproduced the patient's pain.

You CAN'T join if...

  • midline spinal tenderness
  • evidence of radiculopathy
  • pregnant
  • have an allergy to lidocaine
  • altered or deemed incapable of making informed consent
  • had signs of infection or skin breakdown over the trigger point.


  • Emergency Room at UCI Medical Center accepting new patients
    Orange California 92868 United States

Lead Scientist at UC Irvine

  • Bharath Chakravarthy, MD
    Clinical Professor, Emergency Medicine, School of Medicine. Authored (or co-authored) 72 research publications


accepting new patients
Start Date
Completion Date
University of California, Irvine
Phase 4 research study
Study Type
Expecting 110 study participants
Last Updated