Skip to main content

Premature Infant clinical trials at UC Irvine

3 in progress, 2 open to eligible people

Showing trials for
  • Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2

    open to all eligible people

    This study is being done to find out whether umbilical cord milking (UCM) is at least as good as or better than delayed cord clamping (DCC) to reduce bleeding in the brain or prevent death in premature newborns. The investigators will study short and long term outcomes of infants delivered before 32 weeks gestation that receive either UCM or DCC. * The trial was stopped by the DSMB for safety in the small strata. They consequently allowed for continuation of the trial in infants 29-32+6 wk GA.

    Orange, California and other locations

  • Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)

    open to eligible people ages 22 months to 42 months

    An extension of the PREMOD2 trial, the PREMOD2 Follow-Up trial will evaluate the neurodevelopmental outcomes at 22-26 months corrected age of preterm children who received UCM or DCC. This prospective multi-national randomized controlled trial (RCT) is a two-arm parallel non-inferiority design of two alternative approaches of treatment.

    Orange, California and other locations

  • Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants

    Sorry, not currently recruiting here

    This study is being conducted to determine whether prophylactic administration of surfactant by the Less Invasive Surfactant Administration (LISA) method reduces the need for mechanical ventilation in the first 72 hours of life when compared to early Continuous Positive Airway Pressure (CPAP) alone.

    Irvine, California and other locations

Last updated: